منابع مشابه
Dynamics of Transcription Factor Binding Site Evolution
Evolution of gene regulation is crucial for our understanding of the phenotypic differences between species, populations and individuals. Sequence-specific binding of transcription factors to the regulatory regions on the DNA is a key regulatory mechanism that determines gene expression and hence heritable phenotypic variation. We use a biophysical model for directional selection on gene expres...
متن کاملPromoter decoding of transcription factor dynamics
‘Steganography,’ meaning ‘concealed writing,’ is the art of hiding a secret message within another message. The original message appears to be simply a letter or photograph, yet a person with the requisite knowledge can decode it to find hidden information. As it turns out, cells may have developed a form of steganography. Recent studies have shown that a single transcription factor (TF) can ex...
متن کاملDynamics of GATA transcription factor expression during erythroid differentiation.
Although the formation of terminally differentiated erythroid cells has been shown to require the presence of a functional GATA-1 gene in vivo, the role of this transcription factor and other members of the GATA family at earlier stages of erythroid differentiation is unclear. In this report, the expression of GATA-1, GATA-2, and GATA-3 has been examined in enriched peripheral blood progenitors...
متن کاملPlant Defense Gene Regulation and Transcription Factor Dynamics
Plants respond to different pests and pathogens by activating a set of resistance genes that involve in substantial transcriptional reprogramming integrating hormonal, metabolic, and physiological movements [1]. These cumulative downstream defense responses alleviate pathogen and pest by subsequent local or systemic induced resistance. Hormone signaling and trans-acting regulatory factors/ Tran...
متن کاملTranscription factor regulation and chromosome dynamics during pseudohyphal growth
Pseudohyphal growth is a developmental pathway seen in some strains of yeast in which cells form multicellular filaments in response to environmental stresses. We used multiplexed transposon "Calling Cards" to record the genome-wide binding patterns of 28 transcription factors (TFs) in nitrogen-starved yeast. We identified TF targets relevant for pseudohyphal growth, producing a detailed map of...
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ژورنال
عنوان ژورنال: Microbiology
سال: 2008
ISSN: 1350-0872,1465-2080
DOI: 10.1099/mic.0.2008/018549-0